Downregulation of miR-322 promotes apoptosis of GC-2 cell by targeting Ddx3x

Abstract Background Aberrant DNA damage of germ cells, which impairs spermatogenesis and lowers fertility, is an important factor contributing to male infertility. MicroRNAs (miRNAs) play a significant role in the expression and regulation of multiple genes during spermatogenesis. Our previous study...

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Hlavní autoři: Qi Che, Wei Wang, Peng Duan, Fang Fang, Chunyan Liu, Ting Zhou, Honggang Li, Chengling Xiong, Kai Zhao
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2019-08-01
Edice:Reproductive Biology and Endocrinology
Témata:
miR-322
Ddx3x
GC-2 cell
Apoptosis
On-line přístup:http://link.springer.com/article/10.1186/s12958-019-0506-7
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