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Translating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network.

Annotating the genotype-phenotype relationship, and developing a proper quantitative description of the relationship, requires understanding the impact of natural genomic variation on gene expression. We apply a sequence-level model of gap gene expression in the early development of Drosophila to an...

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Huvudupphovsmän: Vitaly V Gursky, Konstantin N Kozlov, Ivan V Kulakovskiy, Asif Zubair, Paul Marjoram, David S Lawrie, Sergey V Nuzhdin, Maria G Samsonova
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2017-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC5595321?pdf=render
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