Identification of IL-6 Signalling Components as Predictors of Severity and Outcome in COVID-19

IL-6 is one of the major mediators of the hyper-inflammatory responses with complex biological functions as it can signal via different modes of action. IL-6 by classical signalling has anti-inflammatory and antibacterial activities, while trans-signalling mediates pro-inflammatory effects. The net...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: María Ángeles Rodríguez-Hernández, David Carneros, María Núñez-Núñez, Ramón Coca, Rosario Baena, Gema M. López-Ruiz, María Elena Cano-Serrano, Alberto Martínez-Tellería, Ana Fuentes-López, Juan Manuel Praena-Fernandez, Christoph Garbers, José Hernández-Quero, Federico García, Stefan Rose-John, Matilde Bustos
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Assuntos:
COVID-19
IL-6
soluble receptors
soluble IL-6 receptor (sIL-6R)
soluble gp130 (sgp130)
IL-6 trans-signalling
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2022.891456/full
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares