A viral genome wide association study and genotypic resistance testing in patients failing first line antiretroviral therapy in the first large countrywide Ethiopian HIV cohort

Abstract Background Antiretroviral therapy (ART) was rolled-out in Ethiopia in 2005, but there are no reports on outcome of ART and human immunodeficiency virus drug resistance (HIVDR) at national level. We described acquired drug resistance mutations in pol gene and performed a viral genome wide as...

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Detalhes bibliográficos
Main Authors: Nigus Fikrie Telele, Amare Worku Kalu, Solomon Gebre-Selassie, Daniel Fekade, Gaetano Marrone, Sebastian Grossmann, Ujjwal Neogi, Belete Tegbaru, Anders Sönnerborg
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-07-01
Colecção:BMC Infectious Diseases
Assuntos:
HIV-1 drug resistance
Near-full length genome
Genome wide association
Antiretroviral therapy
Countrywide HIV cohort
Ethiopia
Acesso em linha:http://link.springer.com/article/10.1186/s12879-019-4196-8
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