PO-20 A HYDROGEN SULFIDE PRODRUG AUGMENTS ANGIOGENESIS IN A SWINE MODEL OF CRITICAL LIMB ISCHEMIA VIA A NITRIC OXIDE DEPENDENT MECHANISM

Introduction: Despite advances in revascularization, treatments for critical limb ischemia (CLI) have been largely unsuccessful. Hydrogen sulfide (H2S) and nitric oxide (NO), are endogenous gasotransmitters which exert potent vasodilatory and proangiogenic effects. Recent experimental evidence sugge...

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Bibliographic Details
Main Authors: Amanda M. Rushing, Amy L. Scarborough, Sarah F. Boisvert, Erminia Donnarumma, Rishi Trivedi, David J. Polhemus, David J. Lefer, Traci T. Goodchild
Format: Artigo
Language:Inglês
Published: BMC 2016-11-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930516/view
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