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LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis.

LKB1 acts as a master upstream protein kinase regulating a number of kinases involved in diverse cellular functions. Recent studies have suggested a role for LKB1 in male fertility. Male mice with reduced total LKB1 expression, including the complete absence of the major splice variant in testis (LK...

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Hlavní autoři: Fiona C Denison, Lee B Smith, Phillip J Muckett, Laura O'Hara, David Carling, Angela Woods
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2011-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3228757?pdf=render
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