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Modeling formamide denaturation of probe-target hybrids for improved microarray probe design in microbial diagnostics.

Application of high-density microarrays to the diagnostic analysis of microbial communities is challenged by the optimization of oligonucleotide probe sensitivity and specificity, as it is generally unfeasible to experimentally test thousands of probes. This study investigated the adjustment of hybr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: L Safak Yilmaz, Alexander Loy, Erik S Wright, Michael Wagner, Daniel R Noguera
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2012-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC3428302?pdf=render
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