Inflammation-Induced Tryptophan Breakdown is Related With Anemia, Fatigue, and Depression in Cancer

Many patients with cancer suffer from anemia, depression, and an impaired quality of life (QoL). These patients often also show decreased plasma tryptophan levels and increased kynurenine concentrations in parallel with elevated concentrations of Th1 type immune activation marker neopterin. In the c...

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Détails bibliographiques
Auteurs principaux: Lukas Lanser, Patricia Kink, Eva Maria Egger, Wolfgang Willenbacher, Dietmar Fuchs, Guenter Weiss, Katharina Kurz
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-02-01
Collection:Frontiers in Immunology
Sujets:
inflammation
tryptophan
kynurenine
cancer
anemia
fatigue
Accès en ligne:https://www.frontiersin.org/article/10.3389/fimmu.2020.00249/full
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