Inflammation-Induced Tryptophan Breakdown is Related With Anemia, Fatigue, and Depression in Cancer

Many patients with cancer suffer from anemia, depression, and an impaired quality of life (QoL). These patients often also show decreased plasma tryptophan levels and increased kynurenine concentrations in parallel with elevated concentrations of Th1 type immune activation marker neopterin. In the c...

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Main Authors: Lukas Lanser, Patricia Kink, Eva Maria Egger, Wolfgang Willenbacher, Dietmar Fuchs, Guenter Weiss, Katharina Kurz
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-02-01
Serier:Frontiers in Immunology
Fag:
inflammation
tryptophan
kynurenine
cancer
anemia
fatigue
Online adgang:https://www.frontiersin.org/article/10.3389/fimmu.2020.00249/full
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