A synergic effect between CYP2C19*2, CYP2C19*3 loss-of-function and CYP2C19*17 gain-of-function alleles is associated with Clopidogrel resistance among Moroccan Acute Coronary Syndromes patients

Abstract Objective The main objective of our study was to investigate the association of CYP2C19*2 and CYP2C19*3 loss-of-function and CYP2C19*17 gain-of-function variants of CYP2C19 gene with Clopidogrel resistance in a sample of Moroccan Acute Coronary Syndromes patients. Results Our results showed...

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Detalhes bibliográficos
Main Authors: Hind Hassani Idrissi, Wiam Hmimech, Nada El Khorb, Hafid Akoudad, Rachida Habbal, Sellama Nadifi
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-01-01
Colecção:BMC Research Notes
Assuntos:
Acute Coronary Syndromes
Clopidogrel response
CYP2C19*2
CYP2C19*3
CYP2C19*17
Moroccan population
Acesso em linha:http://link.springer.com/article/10.1186/s13104-018-3132-0
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