Estimation of immune cell content in tumor using single-cell RNA-seq reference data

Abstract Background The rapid development of single-cell RNA sequencing (scRNA-seq) provides unprecedented opportunities to study the tumor ecosystem that involves a heterogeneous mixture of cell types. However, the majority of previous and current studies related to translational and molecular onco...

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Bibliografiske detaljer
Main Authors: Xiaoqing Yu, Y. Ann Chen, Jose R. Conejo-Garcia, Christine H. Chung, Xuefeng Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-07-01
Serier:BMC Cancer
Fag:
Single-cell RNA-seq
Tumor-infiltrating lymphocyte
Reference gene expression profiles
Head and neck cancer
Online adgang:http://link.springer.com/article/10.1186/s12885-019-5927-3
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