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ANGPTL4 gene E40K variation protects against obesity‐associated dyslipidemia in participants with obesity

Summary Objective ANGPTL4 inhibits lipoprotein lipase in adipose tissue, regulating plasma triglycerides levels. In persons with obesity plasma ANGPTL4 levels have been positively correlated with body fat mass, TG levels and low HDL. A loss‐of‐function E40K mutation in ANGPTL4 prevents LPL inhibitio...

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Main Authors: D. Bailetti, L. Bertoccini, R. M. Mancina, I. Barchetta, D. Capoccia, E. Cossu, A. Pujia, A. Lenzi, F. Leonetti, M. G. Cavallo, S. Romeo, M. G. Baroni
格式: Artigo
語言:Inglês
出版: Wiley 2019-02-01
叢編:Obesity Science & Practice
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在線閱讀:https://doi.org/10.1002/osp4.311
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