ANGPTL4 gene E40K variation protects against obesity‐associated dyslipidemia in participants with obesity

Summary Objective ANGPTL4 inhibits lipoprotein lipase in adipose tissue, regulating plasma triglycerides levels. In persons with obesity plasma ANGPTL4 levels have been positively correlated with body fat mass, TG levels and low HDL. A loss‐of‐function E40K mutation in ANGPTL4 prevents LPL inhibitio...

Full description

Saved in:
Bibliographic Details
Main Authors: D. Bailetti, L. Bertoccini, R. M. Mancina, I. Barchetta, D. Capoccia, E. Cossu, A. Pujia, A. Lenzi, F. Leonetti, M. G. Cavallo, S. Romeo, M. G. Baroni
Format: Artigo
Language:Inglês
Published: Wiley 2019-02-01
Series:Obesity Science & Practice
Subjects:
Genetics
lipoprotein lipase
metabolic healthy obesity (MHO)
triglycerides
Online Access:https://doi.org/10.1002/osp4.311
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items