Dynamic response of microglia/macrophage polarization following demyelination in mice

Abstract Background The glial response in multiple sclerosis (MS), especially for recruitment and differentiation of oligodendrocyte progenitor cells (OPCs), predicts the success of remyelination of MS plaques and return of function. As a central player in neuroinflammation, activation and polarizat...

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Detalhes bibliográficos
Main Authors: Tianci Chu, Yi Ping Zhang, Zhisen Tian, Chuyuan Ye, Mingming Zhu, Lisa B. E. Shields, Maiying Kong, Gregory N. Barnes, Christopher B. Shields, Jun Cai
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-10-01
Colecção:Journal of Neuroinflammation
Assuntos:
Multiple sclerosis
Focal demyelination model
Oligodendrocyte/oligodendrocyte progenitor cells
Microglia/macrophage
Neuroinflammation
Sensorimotor function
Acesso em linha:http://link.springer.com/article/10.1186/s12974-019-1586-1
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