A cost-sensitive online learning method for peptide identification

Abstract Background Post-database search is a key procedure in peptide identification with tandem mass spectrometry (MS/MS) strategies for refining peptide-spectrum matches (PSMs) generated by database search engines. Although many statistical and machine learning-based methods have been developed t...

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Main Authors: Xijun Liang, Zhonghang Xia, Ling Jian, Yongxiang Wang, Xinnan Niu, Andrew J. Link
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-04-01
Serier:BMC Genomics
Fag:
Peptide identification
Mass spectrometry
Classification
Support vector machines
Online learning
Online adgang:http://link.springer.com/article/10.1186/s12864-020-6693-y
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