Circulating lnc-LOC as a novel noninvasive biomarker in the treatment surveillance of acute promyelocytic leukaemia

Abstract Background Acute promyelocytic leukaemia (APL) is a unique subtype of acute myeloid leukaemia (AML) characterized by haematopoietic failure caused by the accumulation of abnormal promyelocytic cells in bone marrow (BM). However, indispensable BM biopsy frequently afflicts patients in leukae...

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Autori principali: Guiran Wang, Guiling Yan, Kanru Sang, Huijie Yang, Ni Sun, Yuanyuan Bai, Feng Xu, Xiaoqun Zheng, Zhanguo Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2022-05-01
Serie:BMC Cancer
Soggetti:
Lnc-LOC
Acute promyelocytic leukaemia
Minimal residual disease
Noninvasive biomarker
Surveillance
Accesso online:https://doi.org/10.1186/s12885-022-09621-1
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