Circulating lnc-LOC as a novel noninvasive biomarker in the treatment surveillance of acute promyelocytic leukaemia

Abstract Background Acute promyelocytic leukaemia (APL) is a unique subtype of acute myeloid leukaemia (AML) characterized by haematopoietic failure caused by the accumulation of abnormal promyelocytic cells in bone marrow (BM). However, indispensable BM biopsy frequently afflicts patients in leukae...

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Main Authors: Guiran Wang, Guiling Yan, Kanru Sang, Huijie Yang, Ni Sun, Yuanyuan Bai, Feng Xu, Xiaoqun Zheng, Zhanguo Chen
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2022-05-01
Series:BMC Cancer
Assuntos:
Lnc-LOC
Acute promyelocytic leukaemia
Minimal residual disease
Noninvasive biomarker
Surveillance
Acceso en liña:https://doi.org/10.1186/s12885-022-09621-1
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