Effect of Substrate Stiffness on Physicochemical Properties of Normal and Fibrotic Lung Fibroblasts

The presented research aims to verify whether physicochemical properties of lung fibroblasts, modified by substrate stiffness, can be used to discriminate between normal and fibrotic cells from idiopathic pulmonary fibrosis (IPF). The impact of polydimethylsiloxane (PDMS) substrate stiffness on the...

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Detalhes bibliográficos
Main Authors: Joanna Raczkowska, Barbara Orzechowska, Sabina Patryas, Kamil Awsiuk, Andrzej Kubiak, Masaya Kinoshita, Masami Okamoto, Justyna Bobrowska, Tomasz Stachura, Jerzy Soja, Krzysztof Sładek, Małgorzata Lekka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-10-01
Colecção:Materials
Assuntos:
idiopathic pulmonary fibrosis
fibroblasts
substrate elasticity
force spectroscopy
Acesso em linha:https://www.mdpi.com/1996-1944/13/20/4495
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