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Targeting the HGF-cMET Axis in Hepatocellular Carcinoma

Under normal physiological conditions, the hepatocyte growth factor (HGF) and its receptor, the MET transmembrane tyrosine kinase (cMET), are involved in embryogenesis, morphogenesis, and wound healing. The HGF-cMET axis promotes cell survival, proliferation, migration, and invasion via modulation o...

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Main Authors: Neeta K. Venepalli, Laura Goff
格式: Artigo
語言:Inglês
出版: Hindawi Limited 2013-01-01
叢編:International Journal of Hepatology
在線閱讀:http://dx.doi.org/10.1155/2013/341636
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