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An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development.

The mechanisms generating stably differentiated cell-types from multipotent precursors are key to understanding normal development and have implications for treatment of cancer and the therapeutic use of stem cells. Pigment cells are a major derivative of neural crest stem cells and a key model cell...

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Detalhes bibliográficos
Main Authors: Emma R Greenhill, Andrea Rocco, Laura Vibert, Masataka Nikaido, Robert N Kelsh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-09-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC3164703?pdf=render
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