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An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development.
The mechanisms generating stably differentiated cell-types from multipotent precursors are key to understanding normal development and have implications for treatment of cancer and the therapeutic use of stem cells. Pigment cells are a major derivative of neural crest stem cells and a key model cell...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science (PLoS)
2011-09-01
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Colecção: | PLoS Genetics |
Acesso em linha: | http://europepmc.org/articles/PMC3164703?pdf=render |
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