Optimization of culture conditions for rapid clinical-scale expansion of human umbilical cord blood-derived mesenchymal stem cells

Abstract Background Mesenchymal stem cells (MSCs) have broad-spectrum therapeutic effects in various diseases, and thus have many clinical applications. However, it is difficult to produce sufficient numbers of MSCs for clinical use, and improved culture systems are required. Here, we report the eff...

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Main Authors: Wankyu Choi, Soon-Jae Kwon, Hye Jin Jin, Sang Young Jeong, Soo Jin Choi, Wonil Oh, Yoon Sun Yang, Hong Bae Jeon, Eun Su Jeon
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2017-10-01
Colecção:Clinical and Translational Medicine
Assuntos:
Calcium
Hypoxia
Human umbilical cord blood-derived mesenchymal stem cells
Clinical-scale culture
Cell therapy
Acesso em linha:http://link.springer.com/article/10.1186/s40169-017-0168-z
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