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Prion Proteins Without the Glycophosphatidylinositol Anchor: Potential Biomarkers in Neurodegenerative Diseases

Prion protein (PrP) is a biomolecule that is involved in neuronal signaling, myelinization, and the development of neurodegenerative diseases. In the cell, PrP is shed by the ADAM10 protease. This process generates PrP molecules that lack glycophosphatidylinositol anchor, and these molecules incorpo...

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Main Authors: Valerija Kovač, Vladka Čurin Šerbec
格式: Artigo
語言:Inglês
出版: SAGE Publishing 2018-02-01
叢編:Biomarker Insights
在線閱讀:https://doi.org/10.1177/1177271918756648
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