Exercise Activates p53 and Negatively Regulates IGF-1 Pathway in Epidermis within a Skin Cancer Model.

Exercise has been previously reported to lower cancer risk through reducing circulating IGF-1 and IGF-1-dependent signaling in a mouse skin cancer model. This study aims to investigate the underlying mechanisms by which exercise may down-regulate the IGF-1 pathway via p53 and p53-related regulators...

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מידע ביבליוגרפי
Main Authors: Miao Yu, Brenee King, Emily Ewert, Xiaoyu Su, Nur Mardiyati, Zhihui Zhao, Weiqun Wang
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2016-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC4979999?pdf=render
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