Extracellular Histones Activate Plasma Membrane Toll-Like Receptor 9 to Trigger Calcium Oscillations in Rat Pancreatic Acinar Tumor Cell AR4-2J

In acute pancreatitis, histones are released by infiltrating neutrophils, but how histones modulate pancreatic acinar cell function has not been investigated. We have examined histone modulation of rat pancreatic acini and pancreatic acinar tumor cell AR4-2J by calcium imaging. Histones were found t...

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Autori principali: Hai Yan Guo, Zong Jie Cui
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2018-12-01
Serie:Cells
Soggetti:
extracellular histones
TLR9
calcium oscillations
AR4-2J
Accesso online:https://www.mdpi.com/2073-4409/8/1/3
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