Extracellular Histones Activate Plasma Membrane Toll-Like Receptor 9 to Trigger Calcium Oscillations in Rat Pancreatic Acinar Tumor Cell AR4-2J

In acute pancreatitis, histones are released by infiltrating neutrophils, but how histones modulate pancreatic acinar cell function has not been investigated. We have examined histone modulation of rat pancreatic acini and pancreatic acinar tumor cell AR4-2J by calcium imaging. Histones were found t...

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Detalles Bibliográficos
Autores principales: Hai Yan Guo, Zong Jie Cui
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2018-12-01
Colección:Cells
Materias:
extracellular histones
TLR9
calcium oscillations
AR4-2J
Acceso en línea:https://www.mdpi.com/2073-4409/8/1/3
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