Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasis

Nearly 40% of the advanced cancer patients will present brain metastases during the course of their disease, with a 2-year life expectancy of less than 10%. Immune system impairment, including the modulation of both STAT3 and PD-L1, is one of the hallmarks of brain metastases. Liquid biopsy could of...

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Detalhes bibliográficos
Main Authors: Alberto Carretero-González, Marta Hergueta-Redondo, Sara Sánchez-Redondo, Pilar Ximénez-Embún, Luis Manso Sánchez, Eva Ciruelos Gil, Daniel Castellano, Guillermo de Velasco, Héctor Peinado
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2022-12-01
Colecção:OncoImmunology
Assuntos:
Small extracellular vesicles
exosomes
brain metastasis
STAT3
PD-L1
Acesso em linha:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2067944
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