Comprehensive transcriptome profiling of BET inhibitor-treated HepG2 cells.

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and poor prognosis. Emerging evidence suggests that epigenetic alterations play a crucial role in HCC, suggesting epigenetic inhibition as a promising therapeutic approach. Indeed, the bromodomain and extra-terminal (BET) inhibit...

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Main Authors: Mina Baek, Jin Choul Chai, Hae In Choi, Eunyoung Yoo, Bert Binas, Young Seek Lee, Kyoung Hwa Jung, Young Gyu Chai
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2022-01-01
Serija:PLoS ONE
Online dostop:https://doi.org/10.1371/journal.pone.0266966
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