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A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity.

Rem2 is a member of the RGK family of small Ras-like GTPases whose expression and function is regulated by neuronal activity in the brain. A number of questions still remain as to the endogenous functions of Rem2 in neurons. RNAi-mediated Rem2 knockdown leads to an increase in dendritic complexity a...

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Xehetasun bibliografikoak
Egile Nagusiak: Anna R Moore, Amy E Ghiretti, Suzanne Paradis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2013-01-01
Saila:PLoS ONE
Sarrera elektronikoa:http://europepmc.org/articles/PMC3753333?pdf=render
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