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A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity.
Rem2 is a member of the RGK family of small Ras-like GTPases whose expression and function is regulated by neuronal activity in the brain. A number of questions still remain as to the endogenous functions of Rem2 in neurons. RNAi-mediated Rem2 knockdown leads to an increase in dendritic complexity a...
Gorde:
Egile Nagusiak: | , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Public Library of Science (PLoS)
2013-01-01
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Saila: | PLoS ONE |
Sarrera elektronikoa: | http://europepmc.org/articles/PMC3753333?pdf=render |
Etiketak: |
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