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Down-Regulation of Insulin Like Growth Factor 1 Involved in Alzheimer’s Disease via MAPK, Ras, and FoxO Signaling Pathways

The inability to halt or even delay the course of Alzheimer’s disease (AD) forces the development of new molecular signatures and therapeutic strategies. Insulin like growth factor 1 (IGF1) is a promising target for AD treatment, yet exact mechanisms of AD ascribed to IGF1 remain elusive. Herein, ge...

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Detalhes bibliográficos
Main Authors: Kexin Kang, Jun Bai, Shanshan Zhong, Rongwei Zhang, Xiaoqian Zhang, Ying Xu, Mei Zhao, Chuansheng Zhao, Zhike Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2022-01-01
Colecção:Oxidative Medicine and Cellular Longevity
Acesso em linha:http://dx.doi.org/10.1155/2022/8169981
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