Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice.

Diabesity-associated metabolic stresses modulate the development of Alzheimer's disease (AD). For further insights into the underlying mechanisms, we examine whether the genetic background of APPswe/PS1dE9 at the prodromal stage of AD affects peripheral metabolism in the context of diabesity. W...

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Hlavní autoři: Feng-Shiun Shie, Young-Ji Shiao, Chih-Wen Yeh, Chien-Hung Lin, Tsai-Teng Tzeng, Hao-Chieh Hsu, Fong-Lee Huang, Huey-Jen Tsay, Hui-Kang Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2015-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4526466?pdf=render
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