NFE2/miR-423-5p/TFF1 axis regulates high glucose-induced apoptosis in retinal pigment epithelial cells

Abstract Background A study has shown that miR-423-5p is highly expressed in proliferative diabetic retinopathy. However, the exact biological functions and mechanisms of miR-423-5p in diabetic retinopathy (DR) progression are currently unclear. This study aimed to investigate the role of miR-423-5p...

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Autori principali: Qing Xiao, Yinu Zhao, Jia Xu, Wen-Jie Li, Yu Chen, Hong-Jing Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2019-08-01
Serie:BMC Molecular and Cell Biology
Soggetti:
Diabetic retinopathy
miR-423-5p
TFF1
NFE2
Retinal pigment epithelial cells
Accesso online:http://link.springer.com/article/10.1186/s12860-019-0223-2
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