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Evaluation of the Protective Effects of Quercetin, Rutin, Naringenin, Resveratrol and Trolox Against Idarubicin-Induced DNA Damage

PURPOSE. Idarubicin is a synthetic anthracycline anticancer drug widely used in the treatment of some hematological malignancies. The studies in our laboratory have clearly demonstrated that idarubicin can undergo reductive bioactivation by NADPH-cytochrome P450 reductase to free radicals with resul...

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Hlavní autoři: Haydar Çelik, Emel Arinç
Médium: Artigo
Jazyk:Inglês
Vydáno: Canadian Society for Pharmaceutical Sciences 2010-07-01
Edice:Journal of Pharmacy & Pharmaceutical Sciences
On-line přístup:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/7167
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