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Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infection.

Acute viral infection causes damages to the host due to uncontrolled viral replication but even replication deficient viral vectors can induce systemic inflammatory responses. Indeed, overactive host innate immune responses to viral vectors have led to devastating consequences. Macrophages are impor...

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Detalhes bibliográficos
Main Authors: Benjamin H Lee, David M Hwang, Nades Palaniyar, Sergio Grinstein, Dana J Philpott, Jim Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3338466?pdf=render
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