Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth

Abstract Background A recent study has shown that it is possible to accurately estimate gestational age (GA) at birth from the DNA methylation (DNAm) of fetal umbilical cord blood/newborn blood spots. This DNAm GA predictor may provide additional information relevant to developmental stage. In 814 m...

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Detalhes bibliográficos
Main Authors: Polina Girchenko, Jari Lahti, Darina Czamara, Anna K. Knight, Meaghan J. Jones, Anna Suarez, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Pia M. Villa, Rebecca M. Reynolds, Michael S. Kobor, Alicia K. Smith, Elisabeth B. Binder, Katri Räikkönen
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-05-01
Colecção:Clinical Epigenetics
Assuntos:
Aging
Cord blood methylation
Epigenetic clock
Gestational age
Prenatal programming
Acesso em linha:http://link.springer.com/article/10.1186/s13148-017-0349-z
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