Dynamic nature of somatic chromosomal mosaicism, genetic-environmental interactions and therapeutic opportunities in disease and aging

Abstract Background Somatic chromosomal mosaicism is the presence of cell populations differing with respect to the chromosome complements (e.g. normal and abnormal) in an individual. Chromosomal mosaicism is associated with a wide spectrum of disease conditions and aging. Studying somatic genome va...

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Hauptverfasser: Svetlana G. Vorsanova, Yuri B. Yurov, Ivan Y. Iourov
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2020-05-01
Schriftenreihe:Molecular Cytogenetics
Schlagworte:
Aneuploidy
Chromosome
Disease
Environment
Ontogeny
Somatic mosaicism
Online Zugang:http://link.springer.com/article/10.1186/s13039-020-00488-0
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