HGF/Met Axis in Heart Function and Cardioprotection

Hepatocyte growth factor (HGF) and its tyrosine kinase receptor (Met) play important roles in myocardial function both in physiological and pathological situations. In the developing heart, HGF influences cardiomyocyte proliferation and differentiation. In the adult, HGF/Met signaling controls hea...

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Bibliographic Details
Main Authors: Simona Gallo, Valentina Sala, Stefano Gatti, Tiziana Crepaldi
Format: Artigo
Language:Inglês
Published: MDPI AG 2014-10-01
Series:Biomedicines
Subjects:
hepatocyte growth factor
Met tyrosine kinase receptor
heart development
cardiotoxicity
cardioprotection
myocardial infarction
angiogenesis
fibrosis
inflammation
cardiac regeneration
Online Access:http://www.mdpi.com/2227-9059/2/4/247
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