Novel Protein–Protein Interactions Highlighting the Crosstalk between Hypoplastic Left Heart Syndrome, Ciliopathies and Neurodevelopmental Delays

Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease (CHD) affecting 1 in 5000 newborns. We constructed the interactome of 74 HLHS-associated genes identified from a large-scale mouse mutagenesis screen, augmenting it with 408 novel protein–protein interactions (PPIs) using ou...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Kalyani B. Karunakaran, George C. Gabriel, Narayanaswamy Balakrishnan, Cecilia W. Lo, Madhavi K. Ganapathiraju
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-04-01
Series:Genes
Assuntos:
protein–protein interactions
interactome
congenital heart disease
developmental disorder
hypoplastic left heart syndrome
web application
Acceso en liña:https://www.mdpi.com/2073-4425/13/4/627
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares