Impact of Cerebral Amyloid Angiopathy in Two Transgenic Mouse Models of Cerebral β-Amyloidosis: A Neuropathological Study

The pathological accumulation of parenchymal and vascular amyloid-beta (Aβ) are the main hallmarks of Alzheimer’s disease (AD) and Cerebral Amyloid Angiopathy (CAA), respectively. Emerging evidence raises an important contribution of vascular dysfunction in AD pathology that could partially explain...

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Main Authors: Paula Marazuela, Berta Paez-Montserrat, Anna Bonaterra-Pastra, Montse Solé, Mar Hernández-Guillamon
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Assuntos:
APP23
5xFAD
cerebral β-amyloidosis
preclinical MRI
cerebral microbleeds
Acceso en liña:https://www.mdpi.com/1422-0067/23/9/4972
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