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Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?
Cells expressing IDO suppress innate and adaptive immunity to promote tolerance by catabolizing the amino acid tryptophan (Trp) and other indole compounds. Interferon type I (IFN-I) and type II (IFN-II) produced at sites of inflammation or by activated immune cells are potent IDO inducers because ma...
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| Main Authors: | , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2017-10-01
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| 叢編: | Frontiers in Immunology |
| 主題: | |
| 在線閱讀: | http://journal.frontiersin.org/article/10.3389/fimmu.2017.01360/full |
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