Influence of exogenous growth hormone administration on circulating concentrations of α-klotho in healthy and chronic kidney disease subjects: a prospective, single-center open case-control pilot study

Abstract Background The CKD-associated decline in soluble α-Klotho (α-Klotho) levels is considered detrimental. Some studies suggest a direct induction of α-Klotho concentrations by growth hormone (GH). In the present study, the effect of exogenous GH administration on α-Klotho concentrations in a c...

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Main Authors: Aaltje Y. Adema, Camiel L. M. de Roij van Zuijdewijn, Joost G. Hoenderop, Martin H. de Borst, Piet M. Ter Wee, Annemieke C. Heijboer, Marc G. Vervloet, for the NIGRAM consortium
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-11-01
Colecção:BMC Nephrology
Assuntos:
α-Klotho
Growth hormone
Chronic kidney disease
Acesso em linha:http://link.springer.com/article/10.1186/s12882-018-1114-z
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