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The Salmonella deubiquitinase SseL inhibits selective autophagy of cytosolic aggregates.

Cell stress and infection promote the formation of ubiquitinated aggregates in both non-immune and immune cells. These structures are recognised by the autophagy receptor p62/sequestosome 1 and are substrates for selective autophagy. The intracellular growth of Salmonella enterica occurs in a membra...

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Hlavní autoři: Francisco S Mesquita, Mair Thomas, Martin Sachse, António J M Santos, Rita Figueira, David W Holden
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS Pathogens
On-line přístup:http://europepmc.org/articles/PMC3375275?pdf=render
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