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Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair

Abstract Background Olfactory ensheathing cells (OEC), specialized glia that ensheathe bundles of olfactory nerves, have been reported as a favorable substrate for axonal regeneration. Grafting OEC to injured spinal cord appears to facilitate axonal regeneration although the functional recovery is l...

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Auteurs principaux: May-Jywan Tsai, Chi-Ting Huang, Yong-San Huang, Ching-Feng Weng, Song-Kun Shyue, Ming-Chao Huang, Dann-Ying Liou, Yan-Ru Lin, Chu-Hsun Cheng, Huai-Sheng Kuo, Yilo Lin, Meng-Jen Lee, Wen-Hung Huang, Wen-Cheng Huang, Henrich Cheng
Format: Artigo
Langue:Inglês
Publié: BMC 2017-05-01
Collection:Journal of Biomedical Science
Sujets:
Prostacyclin
Gene transfer
Transplantation
Spinal nerve regeneration
Olfactory ensheathing glia
Accès en ligne:http://link.springer.com/article/10.1186/s12929-017-0340-1
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