APPLIED ASPECTS OF SLCO1B1 PHARMACOGENETIC TESTING FOR PREDICTING OF STATIN-INDUCED MYOPATHY AND PERSONALIZATION OF STATINS THERAPY

The clinical significance of the SLCO1B1 gene polymorphism (encoding an organic anion transport polipeptide) in the development of statin induced myopathy is considered. Possible tactics of statin dose determination on the basis of pharmacogenetic testing is discussed. Indications for the use of thi...

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Main Authors: D. A. Sychev, G. N. Shuev, A. B. Prokofiev
Formato: Artigo
Idioma:Inglês
Publicado em: Stolichnaya Izdatelskaya Kompaniya 2015-09-01
Colecção:Racionalʹnaâ Farmakoterapiâ v Kardiologii
Assuntos:
pharmacogenetics
statins
myopathy
slco1b1
personalized medicine
Acesso em linha:https://www.rpcardio.com/jour/article/view/299
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