HALC: High throughput algorithm for long read error correction

Abstract Background The third generation PacBio SMRT long reads can effectively address the read length issue of the second generation sequencing technology, but contain approximately 15% sequencing errors. Several error correction algorithms have been designed to efficiently reduce the error rate t...

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Main Authors: Ergude Bao, Lingxiao Lan
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-04-01
Serier:BMC Bioinformatics
Fag:
PacBio long reads
Error correction
Throughput
Online adgang:http://link.springer.com/article/10.1186/s12859-017-1610-3
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