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Post-translational Modifications of the Peptidyl-Prolyl Isomerase Pin1

The peptidyl-prolyl cis/trans isomerase (PPIase) Pin1 is a unique enzyme that only binds to Ser/Thr-Pro peptide motifs after phosphorylation and regulates the conformational changes of the bond. The Pin1-catalyzed isomerization upon phosphorylation can have profound effects on substrate biological f...

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Main Authors: Dongmei Chen, Long Wang, Tae Ho Lee
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020-03-01
叢編:Frontiers in Cell and Developmental Biology
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在線閱讀:https://www.frontiersin.org/article/10.3389/fcell.2020.00129/full
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