Elucidation of the Effects of a Current X-SCID Therapy on Intestinal Lymphoid Organogenesis Using an In Vivo Animal ModelSummary

Background & Aims: Organ-level research using an animal model lacking Il2rg, the gene responsible for X-linked severe combined immunodeficiency (X-SCID), is clinically unavailable and would be a powerful tool to gain deeper insights into the symptoms of patients with X-SCID. Methods: We used...

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Main Authors: Tomonori Nochi, Shunichi Suzuki, Shun Ito, Shotaro Morita, Mutsumi Furukawa, Daiichiro Fuchimoto, Yoji Sasahara, Katsuki Usami, Kanae Niimi, Osamu Itano, Minoru Kitago, Sachiko Matsuda, Ayumi Matsuo, Yoshihisa Suyama, Yoshifumi Sakai, Guoyao Wu, Fuller W. Bazer, Kouichi Watanabe, Akira Onishi, Hisashi Aso
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-01-01
Colecção:Cellular and Molecular Gastroenterology and Hepatology
Assuntos:
Peyer’s Patches
IgA
Microflora
X-SCID
BMT
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352345X20300187
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