Targeting Stress Sensor Kinases in Hepatocellular Carcinoma-Infiltrating Human NK Cells as a Novel Immunotherapeutic Strategy for Liver Cancer

Natural killer (NK) cells may become functionally exhausted entering hepatocellular carcinoma (HCC), and this has been associated with tumor progression and poor clinical outcome. Hypoxia, low nutrients, immunosuppressive cells, and soluble mediators characterize the intratumor microenvironment res...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Alessandra Zecca, Valeria Barili, Andrea Olivani, Elisabetta Biasini, Carolina Boni, Paola Fisicaro, Ilaria Montali, Camilla Tiezzi, Raffaele Dalla Valle, Carlo Ferrari, Elisabetta Cariani, Gabriele Missale
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2022-05-01
श्रृंखला:Frontiers in Immunology
विषय:
immunometabolism
NK-cell
immunotherapy
hepatocellular carcinoma
oncoimmunology
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fimmu.2022.875072/full
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