Targeting Stress Sensor Kinases in Hepatocellular Carcinoma-Infiltrating Human NK Cells as a Novel Immunotherapeutic Strategy for Liver Cancer

Natural killer (NK) cells may become functionally exhausted entering hepatocellular carcinoma (HCC), and this has been associated with tumor progression and poor clinical outcome. Hypoxia, low nutrients, immunosuppressive cells, and soluble mediators characterize the intratumor microenvironment res...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Alessandra Zecca, Valeria Barili, Andrea Olivani, Elisabetta Biasini, Carolina Boni, Paola Fisicaro, Ilaria Montali, Camilla Tiezzi, Raffaele Dalla Valle, Carlo Ferrari, Elisabetta Cariani, Gabriele Missale
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2022-05-01
Sarja:Frontiers in Immunology
Aiheet:
immunometabolism
NK-cell
immunotherapy
hepatocellular carcinoma
oncoimmunology
Linkit:https://www.frontiersin.org/articles/10.3389/fimmu.2022.875072/full
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