Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets.

Genome-wide association studies have mainly relied on common HapMap sequence variations. Recently, sequencing approaches have allowed analysis of low frequency and rare variants in conjunction with common variants, thereby improving the search for functional variants and thus the understanding of th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Niels Grarup, Patrick Sulem, Camilla H Sandholt, Gudmar Thorleifsson, Tarunveer S Ahluwalia, Valgerdur Steinthorsdottir, Helgi Bjarnason, Daniel F Gudbjartsson, Olafur T Magnusson, Thomas Sparsø, Anders Albrechtsen, Augustine Kong, Gisli Masson, Geng Tian, Hongzhi Cao, Chao Nie, Karsten Kristiansen, Lise Lotte Husemoen, Betina Thuesen, Yingrui Li, Rasmus Nielsen, Allan Linneberg, Isleifur Olafsson, Gudmundur I Eyjolfsson, Torben Jørgensen, Jun Wang, Torben Hansen, Unnur Thorsteinsdottir, Kari Stefánsson, Oluf Pedersen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2013-06-01
Cyfres:PLoS Genetics
Mynediad Ar-lein:http://europepmc.org/articles/PMC3674994?pdf=render
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