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Isosteviol Sensitizes sarcKATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes

KATP channel is an important mediator or factor in physiological and pathological metabolic pathway. Activation of KATP channel has been identified to be a critical step in the cardioprotective mechanism against IR injury. On the other hand, desensitization of the channel to its opener or the metabo...

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Detalhes bibliográficos
Main Authors: Zhuo Fan, Ting Wen, Yaoxu Chen, Lijie Huang, Wei Lin, Chunxia Yin, Wen Tan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2016-01-01
Colecção:Oxidative Medicine and Cellular Longevity
Acesso em linha:http://dx.doi.org/10.1155/2016/6362812
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