Date palm seed extract and herbal mixture mitigate gentamicin-induced renal injury in mice: Role of Protease-activated receptors (PARs) and Retinoid X receptor alpha (RXR-α)

Introduction: Gentamicin (Gen) causes renal toxicity by inhibiting protein synthesis in kidney cells, causing proximal tubule cell necrosis and renal failure. Herein, we examined the nephroprotective effect of date palm seed extract (DPSE) and one herbal mixture (HM; composed of Tribulus terrestris,...

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Main Authors: Suliman Sohaim, Salman Mohammed, Elham Amin, Hussein M Ali, Mohamed Abdelbakky
Formato: Artigo
Idioma:Inglês
Publicado em: Shahrekord University of Medical Sciences 2022-04-01
Colecção:Journal of HerbMed Pharmacology
Assuntos:
nephroprotection
renal toxicity
gentamycin
renal injury
histopathology
phoenix dactylifera
Acesso em linha:http://herbmedpharmacol.com/PDF/jhp-11-286.pdf
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